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William D Figg Selected Research

romidepsin (FK228)

11/2016Pharmacogenomics and histone deacetylase inhibitors.
8/2013Phase I trial of a new schedule of romidepsin in patients with advanced cancers.
6/2013Electrocardiographic studies of romidepsin demonstrate its safety and identify a potential role for K(ATP) channel.
6/2011Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma.
7/2010Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors.
1/2010Laboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma.
11/2009Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma.
2/2009Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma.
1/2008Clinical and molecular responses in lung cancer patients receiving Romidepsin.
9/2004Determination of the cyclic depsipeptide FK228, a histone deacetylase inhibitor, by liquid chromatography-mass spectrometry.
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William D Figg Research Topics

Disease

225Neoplasms (Cancer)
12/2022 - 01/2002
172Prostatic Neoplasms (Prostate Cancer)
12/2022 - 01/2002
23Neoplasm Metastasis (Metastasis)
11/2020 - 01/2002
22Disease Progression
11/2022 - 05/2005
20Breast Neoplasms (Breast Cancer)
06/2021 - 02/2003
16Multiple Myeloma
11/2021 - 11/2004
15Hypoxia (Hypoxemia)
01/2021 - 09/2003
14Carcinoma (Carcinomatosis)
11/2022 - 10/2003
13Neutropenia
01/2021 - 05/2002
10Diarrhea
01/2021 - 02/2003
9Fatigue
01/2021 - 05/2002
8Thrombocytopenia (Thrombopenia)
11/2021 - 05/2005
7Carcinogenesis
01/2018 - 06/2002
7Renal Cell Carcinoma (Grawitz Tumor)
01/2015 - 07/2004
6Pain (Aches)
10/2020 - 02/2003
6Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
04/2016 - 02/2009
6Lymphoma (Lymphomas)
11/2014 - 06/2005
5Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 06/2007
5Infections
12/2021 - 07/2010
5Ovarian Neoplasms (Ovarian Cancer)
06/2021 - 08/2008
5Lung Neoplasms (Lung Cancer)
11/2020 - 04/2002
5Melanoma (Melanoma, Malignant)
11/2020 - 06/2007
5Hypertension (High Blood Pressure)
07/2017 - 02/2009
5T-Cell Lymphoma (Lymphoma, T Cell)
08/2013 - 02/2009
4Osteonecrosis (Kienbock's Disease)
12/2021 - 02/2009
4Brain Neoplasms (Brain Tumor)
12/2021 - 06/2003
4Glioma (Gliomas)
12/2021 - 06/2003
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2020 - 09/2007
4Kaposi Sarcoma (Kaposi's Sarcoma)
01/2020 - 01/2002
4Colorectal Neoplasms (Colorectal Cancer)
12/2019 - 11/2004
4Glioblastoma (Glioblastoma Multiforme)
01/2018 - 12/2013

Drug/Important Bio-Agent (IBA)

57AndrogensIBA
01/2022 - 05/2002
51Pharmaceutical PreparationsIBA
01/2022 - 04/2002
32Thalidomide (Thalomid)FDA Link
01/2018 - 02/2002
31Docetaxel (Taxotere)FDA Link
01/2021 - 01/2003
29Androgen Receptors (Androgen Receptor)IBA
01/2021 - 01/2002
28Biomarkers (Surrogate Marker)IBA
11/2022 - 05/2002
20Hormones (Hormone)IBA
01/2022 - 05/2002
20Proteins (Proteins, Gene)FDA Link
06/2019 - 04/2002
18Prostate-Specific Antigen (Semenogelase)IBA
01/2020 - 09/2002
18Histone Deacetylase InhibitorsIBA
01/2020 - 03/2002
17Lenalidomide (CC 5013)FDA Link
11/2021 - 05/2002
17Paclitaxel (Taxol)FDA LinkGeneric
06/2021 - 04/2002
15Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019 - 01/2002
14VA 061 (VA061)IBA
12/2008 - 01/2003
13Sorafenib (BAY 43-9006)FDA Link
11/2021 - 10/2006
13Angiogenesis InhibitorsIBA
10/2014 - 05/2002
12Finasteride (Propecia)FDA LinkGeneric
01/2022 - 04/2008
12olaparibIBA
04/2021 - 06/2014
12Testosterone (Sustanon)FDA Link
01/2017 - 03/2006
12romidepsin (FK228)FDA Link
11/2016 - 03/2002
12Bevacizumab (Avastin)FDA Link
10/2016 - 08/2008
11EnzymesIBA
12/2022 - 03/2002
11alvocidib (flavopiridol)IBA
01/2019 - 05/2002
10DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2002
10Transcription Factors (Transcription Factor)IBA
09/2017 - 09/2003
9Prednisone (Sone)FDA LinkGeneric
01/2021 - 02/2009
9entinostat (MS 275)IBA
01/2020 - 05/2004
7Biological ProductsIBA
01/2022 - 08/2004
7Interleukin-15 (Interleukin 15)IBA
11/2021 - 05/2011
7Dexamethasone (Maxidex)FDA LinkGeneric
11/2021 - 01/2017
7belinostatIBA
01/2018 - 11/2014
7Antineoplastic Agents (Antineoplastics)IBA
11/2009 - 05/2002
6enzalutamideIBA
12/2022 - 06/2015
6SteroidsIBA
01/2022 - 12/2008
6carfilzomibIBA
11/2021 - 01/2017
6Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2021 - 07/2008
6PlatinumIBA
01/2020 - 07/2008
6CytochromesIBA
01/2020 - 10/2005
6Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
01/2020 - 08/2007
6Estrogens (Estrogen)FDA Link
01/2018 - 12/2003
6Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
06/2017 - 10/2005
6DepsipeptidesIBA
06/2011 - 03/2002
5Diphosphonates (Bisphosphonates)IBA
12/2021 - 12/2002
5Tyrosine Kinase InhibitorsIBA
11/2021 - 08/2004
5abirateroneIBA
01/2021 - 12/2014
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2019 - 12/2004
5Carboplatin (JM8)FDA LinkGeneric
04/2019 - 06/2014
5carotuximabIBA
08/2017 - 09/2012
5EndoglinIBA
08/2017 - 09/2012
5Member 1 Subfamily B ATP Binding Cassette TransporterIBA
02/2011 - 07/2004
5Matrix Metalloproteinases (MMPs)IBA
06/2004 - 01/2002
4CamptothecinIBA
01/2022 - 03/2020
4Immune Checkpoint InhibitorsIBA
01/2022 - 01/2015
4cabozantinibIBA
01/2022 - 01/2020
4IT-101IBA
01/2022 - 03/2020
4Temozolomide (Temodar)FDA LinkGeneric
12/2021 - 10/2014
4taxaneIBA
06/2021 - 04/2002
4Immunomodulating AgentsIBA
01/2021 - 06/2007
4pomalidomideIBA
01/2021 - 06/2007
4ProdrugsIBA
01/2021 - 12/2017
4CytokinesIBA
01/2020 - 01/2015
4cediranib (AZD2171)IBA
01/2019 - 06/2013
4Cytotoxins (Cytolysins)IBA
01/2019 - 06/2003

Therapy/Procedure

100Therapeutics
12/2022 - 04/2002
49Castration
12/2022 - 09/2007
30Drug Therapy (Chemotherapy)
12/2021 - 01/2003
9Radiotherapy
01/2021 - 02/2004
4Immunotherapy
01/2022 - 01/2015
4Precision Medicine
04/2021 - 01/2017